Ituricoxib Tablets 120 mg
What is ituricoxib and what it is used for:
Etoricoxib is one of a group of drugs called selective COX-2 inhibitors. These belong to a family of drugs called non-steroidal anti-inflammatory drugs (NSAIDs).
What are the uses of etoricoxib?
• Etoricoxib helps reduce pain and swelling (inflammation) in the joints and muscles of people aged 16 years and older with osteoporosis, rheumatoid arthritis, ankylosing spondylitis and gout.
• Etoricoxib is also indicated for the short-term treatment of moderate pain after dental surgery in people aged 16 years and older.
What is arthritis?
• Osteoarthritis is a disease of the joints. It results from the gradual breakdown of the cartilage that clogs the ends of the bones. This causes swelling (inflammation), pain, tenderness, stiffness and impotence.
What is rheumatoid arthritis?
• Rheumatoid arthritis is a long-term inflammatory disease of the joints. It causes pain, stiffness, swelling and increased loss of mobility in the joints it afflicts. It may also cause inflammation in other areas of the body.
What is gout?
• Gout is a disease caused by sudden and frequent episodes of very painful inflammation and redness of the joints. It occurs due to deposits of mineral crystals in the joint.
What is ankylosing spondylitis?
• Ankylosing spondylitis is an inflammatory disease of the spine and large joints.
What you need to know before using ituricoxib :
Do not use ituricoxib:
Tell your doctor if you:
• if you are allergic (hypersensitive) to etoricoxib or any of the other ingredients of this medicine
• if you are allergic to non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin and COX-2 inhibitors
• If you have a stomach ulcer or bleeding in the stomach or intestines
• If you have serious liver disease
• If you have serious kidney disease
• If you are pregnant or could be pregnant or breastfeeding
• If you are under 16 years of age
• If you have inflammatory bowel disease, such as Crohn's disease, ulcerative colitis or colitis
if you have high blood pressure that has not been controlled by treatment (consult your doctor or nurse if you are not sure if your blood pressure is adequately controlled)
• If your doctor diagnoses heart problems including heart failure (moderate or severe types) and angina (chest pain)
• if you have had a heart attack, bypass surgery or peripheral artery disease (poor circulation in the legs or feet due to narrowed or blocked arteries)
• If you have had any type of stroke (including a small stroke, TIA or TIA). Etoricoxib may slightly increase the risk of heart attack and stroke and for this reason it should not be used in those who already have heart problems or stroke.
Warnings and precautions:
You should tell your doctor the following:
• You have a history of stomach bleeding or ulcers.
• You are dehydrated, for example due to a prolonged bout of vomiting or diarrhea.
• You have swelling due to fluid retention.
• You have a history of heart failure, or any other form of heart disease.
• You have a history of high blood pressure. Ittoricoxib can increase blood pressure in some people, especially in high doses, and your doctor will want to check your blood pressure from time to time.
• Have any history of liver or kidney disease.
• You are being treated for an infection. Etoricoxib can hide or hide fever, which is a sign of infection.
• You have diabetes, high cholesterol, or a smoker. They can increase the risk of heart disease.
• You are a woman trying to get pregnant.
• You are over 65 years old.
Other medicines and etoricoxib:
Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including over-the-counter medications.
• medicines that thin the blood (anticoagulants), such as warfarin
• rifampicin (antibiotic)
methotrexate (a medicine used to suppress the immune system, often used in rheumatoid arthritis)
• cyclosporine or tacrolimus (medicines used to suppress the immune system)
• Lithium (a medicine used to treat some types of depression)
medicines used to help control high blood pressure and heart failure are called ACE inhibitors and angiotensin receptor blockers, examples of which are enalapril, ramipril, losartan and valsartan
• Diuretics (water tablets)
• Digoxin (medicine for heart failure and arrhythmias)
• Minoxidil (a medicine used to treat high blood pressure)
• Salbutamol tablets or oral solution (medicine for asthma)
• birth control pills (combination may increase the risk of side effects)
hormone replacement therapy (combination may increase the risk of side effects)
• Aspirin, the risk of stomach ulcers is greater if you take ituricoxib with aspirin.
• Aspirin to prevent heart attacks or strokes:
• Etoricoxib can be taken at a low dose of aspirin.
If you are currently taking low-dose aspirin to prevent heart attack or stroke, you should not stop taking aspirin until you speak to your doctor
• Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs):
• Do not take high-dose aspirin or other anti-inflammatory drugs while taking ituricoxib.
How to use ituricoxib:
Always takethis medicine exactly as your doctor told you. Consult your doctor or pharmacist if you are not sure.
• Do not take more than the recommended dose for your condition. Your doctor will want to discuss your treatment from time to time.
• It is important that you use the lowest dose that controls your pain and you should not take ituricoxib for longer than necessary.
This is because the risk of heart attacks and strokes may increase after prolonged treatment, especially with high doses.
The recommended dose is:
Rheumatoid arthritis
• The recommended dose is 60 mg once a day, increasing to 90 mg once daily if necessary.
Spondylitis
• The recommended dose is 60 mg once a day, increasing to 90 mg once daily if necessary.
Acute pain cases
• Etoricoxib should be used only for the period of acute pain.
Gout
• The recommended dose is 120 mg once a day which should only be used for the acute pain period, a maximum of 8 days of treatment.
Post-dental pain
• The recommended dose is 90 mg once daily, a maximum of 3 treatment days.
People with liver problems
• If you have mild liver disease, you should not take more than 60 mg per day.
• If you have moderate liver disease, you should not take more than 30 mg per day.
Use in children and adolescents
• Etoricoxib tablets should not be taken in children or adolescents under the age of 16.
seniors
• No dose adjustment is required for elderly patients. As with other drugs, caution should be exercised in elderly patients.
Method of administration
• Etoricoxib for oral use. Take tablets once a day. Etoricoxib can be taken with or without food.
Possible side effects:
• Discontinue use and seek immediate medical attention if you develop any of the following signs
• the appearance of shortness of breath, chest pain, ankle swelling or if it worsens
• Yellowing of the skin and eyes (jaundice) - these are signs of liver problems
• Severe or persistent stomach pain or blackening stools
an allergic reaction – which can include skin problems such as ulcers or pimples, swelling of the face, lips, tongue or throat which may cause difficulty breathing
How to store ituricoxib:
• Keep this medicine out of the sight and reach of children.
• Do not use this medicine after the expiration date stated on the carton.
• The expiration date refers to the last day of the same month.
• Bottles: Keep the container tightly closed to protect it from moisture.
• Pimples: Store in the original box to protect it from moisture.
• Do not dispose of medicines in wastewater or household waste.
• Ask your pharmacist how to dispose of medicines you no longer use. These measures will help protect the environment.